| pubmed-article:15915152 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15915152 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:15915152 | lifeskim:mentions | umls-concept:C0920472 | lld:lifeskim |
| pubmed-article:15915152 | lifeskim:mentions | umls-concept:C1450477 | lld:lifeskim |
| pubmed-article:15915152 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:15915152 | pubmed:dateCreated | 2005-6-2 | lld:pubmed |
| pubmed-article:15915152 | pubmed:abstractText | The focus of innovation in current drug discovery is on new targets, yet compound efficacy and safety in biological models of disease - not target selection - are the criteria that determine which drug candidates enter the clinic. We consider a biology-driven approach to drug discovery that involves screening compounds by automated response profiling in disease models based on complex human-cell systems. Drug discovery through cell systems biology could significantly reduce the time and cost of new drug development. | lld:pubmed |
| pubmed-article:15915152 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15915152 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15915152 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15915152 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15915152 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15915152 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15915152 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:15915152 | pubmed:issn | 1474-1776 | lld:pubmed |
| pubmed-article:15915152 | pubmed:author | pubmed-author:ButcherEugene... | lld:pubmed |
| pubmed-article:15915152 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15915152 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:15915152 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15915152 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15915152 | pubmed:pagination | 461-7 | lld:pubmed |
| pubmed-article:15915152 | pubmed:dateRevised | 2007-2-15 | lld:pubmed |
| pubmed-article:15915152 | pubmed:meshHeading | pubmed-meshheading:15915152... | lld:pubmed |
| pubmed-article:15915152 | pubmed:meshHeading | pubmed-meshheading:15915152... | lld:pubmed |
| pubmed-article:15915152 | pubmed:meshHeading | pubmed-meshheading:15915152... | lld:pubmed |
| pubmed-article:15915152 | pubmed:meshHeading | pubmed-meshheading:15915152... | lld:pubmed |
| pubmed-article:15915152 | pubmed:meshHeading | pubmed-meshheading:15915152... | lld:pubmed |
| pubmed-article:15915152 | pubmed:meshHeading | pubmed-meshheading:15915152... | lld:pubmed |
| pubmed-article:15915152 | pubmed:meshHeading | pubmed-meshheading:15915152... | lld:pubmed |
| pubmed-article:15915152 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15915152 | pubmed:articleTitle | Can cell systems biology rescue drug discovery? | lld:pubmed |
| pubmed-article:15915152 | pubmed:affiliation | Department of Pathology, Stanford University, Stanford, California 94305-5324, USA. ebutcher@stanford.edu | lld:pubmed |
| pubmed-article:15915152 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15915152 | pubmed:publicationType | Review | lld:pubmed |
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