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pubmed-article:15914110pubmed:abstractTextExperimental evidence suggests that modulation of myocardial substrate metabolism can markedly affect the progression of chronic heart failure (HF). We tested whether the inhibition of carnitine palmitoyl transferase-I (CPT-I), the enzyme regulating mitochondrial fatty acid oxidation, slows left ventricular remodeling and deterioration of function in pacing-induced HF.lld:pubmed
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pubmed-article:15914110pubmed:articleTitleCarnitine palmitoyl transferase-I inhibition prevents ventricular remodeling and delays decompensation in pacing-induced heart failure.lld:pubmed
pubmed-article:15914110pubmed:affiliationDepartment of Physiology, BSB 622, New York Medical College, Valhalla, 10595, USA.lld:pubmed
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