Linked Life Data

15914003

Source:http://linkedlifedata.com/resource/pubmed/id/15914003

Statements in which the resource exists.
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pubmed-article:15914003pubmed:abstractTextA series of Ge132 derivatives have shown enhanced antitumor activity. Previous studies suggest that DNA can be their primary target. Here we show direct evidence that two newly synthesized Ge132 derivatives can intercalate into DNA. Unexpected methyl substitution effect of the novel derivatives on DNA sequence selectivity and cytotoxicity was observed.lld:pubmed
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pubmed-article:15914003pubmed:articleTitleDNA binding specificity and cytotoxicity of novel antitumor agent Ge132 derivatives.lld:pubmed
pubmed-article:15914003pubmed:affiliationDivision of Biological Inorganic Chemistry, Key Laboratory of Rare Earth Chemistry and Physics, Graduate School of the Chinese Academy of Sciences, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.lld:pubmed
pubmed-article:15914003pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15914003pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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