| pubmed-article:1590828 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1590828 | lifeskim:mentions | umls-concept:C2349001 | lld:lifeskim |
| pubmed-article:1590828 | lifeskim:mentions | umls-concept:C0681850 | lld:lifeskim |
| pubmed-article:1590828 | lifeskim:mentions | umls-concept:C1706203 | lld:lifeskim |
| pubmed-article:1590828 | lifeskim:mentions | umls-concept:C2697811 | lld:lifeskim |
| pubmed-article:1590828 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:1590828 | lifeskim:mentions | umls-concept:C0003593 | lld:lifeskim |
| pubmed-article:1590828 | lifeskim:mentions | umls-concept:C1550501 | lld:lifeskim |
| pubmed-article:1590828 | lifeskim:mentions | umls-concept:C0598528 | lld:lifeskim |
| pubmed-article:1590828 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1590828 | pubmed:dateCreated | 1992-6-24 | lld:pubmed |
| pubmed-article:1590828 | pubmed:abstractText | Utilising a combination of m-aminophenyl-borate affinity chromatography and an immunoradiometric assay for apolipoprotein B (apo B), we have developed a specific and highly sensitive (6 ng/ml) procedure for the assay of glycated apo B. We studied 52 diabetic patients, 50 non-diabetic control subjects and 12 patients heterozygous for familial hypercholesterolaemia (FH). Both insulin-dependent and non-insulin dependent diabetics were included in our study. Total apo B in the diabetics (108 +/- 5 mg/dl; mean +/- S.E.M) was increased (controls: 95 +/- 4 mg/dl; P less than 0.05). In the FH group the serum apo B concentration (216 +/- 24 mg/dl) was significantly higher (P less than 0.001) than both the other groups studied. Both the serum glycated apo B concentration (9.3 +/- 0.8 mg/dl versus 4.8 +/- 0.7 mg/dl) and the percentage glycated apo B (7.9 +/- 0.4% compared to 3.9 +/- 0.2%) were significantly higher in the diabetics than in non-diabetic controls (P less than 0.001). A positive correlation was found between the percentage of glycated apo B and glycated haemoglobin (r = 0.65; P less than 0.001) and fasting glucose concentration (r = 0.52; P less than 0.001) in diabetics. The percentage of glycated apo B in FH patients was not significantly different from controls, but the serum concentration of glycated apo B, because of the greatly increased total level of apo B was raised (8.2 +/- 1.4 mg/dl) to a similar extent to that of the diabetics. | lld:pubmed |
| pubmed-article:1590828 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1590828 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1590828 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1590828 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1590828 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1590828 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:1590828 | pubmed:issn | 0021-9150 | lld:pubmed |
| pubmed-article:1590828 | pubmed:author | pubmed-author:DurringtonP... | lld:pubmed |
| pubmed-article:1590828 | pubmed:author | pubmed-author:LaingII | lld:pubmed |
| pubmed-article:1590828 | pubmed:author | pubmed-author:ArrolSS | lld:pubmed |
| pubmed-article:1590828 | pubmed:author | pubmed-author:TamesF JFJ | lld:pubmed |
| pubmed-article:1590828 | pubmed:author | pubmed-author:MacknessM IMI | lld:pubmed |
| pubmed-article:1590828 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1590828 | pubmed:volume | 93 | lld:pubmed |
| pubmed-article:1590828 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1590828 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1590828 | pubmed:pagination | 237-44 | lld:pubmed |
| pubmed-article:1590828 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:meshHeading | pubmed-meshheading:1590828-... | lld:pubmed |
| pubmed-article:1590828 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1590828 | pubmed:articleTitle | Non-enzymatic glycation of apolipoprotein B in the sera of diabetic and non-diabetic subjects. | lld:pubmed |
| pubmed-article:1590828 | pubmed:affiliation | Department of Clinical Biochemistry, Manchester Royal Infirmary, UK. | lld:pubmed |
| pubmed-article:1590828 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1590828 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1590828 | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1590828 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1590828 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1590828 | lld:pubmed |
