| pubmed-article:15906538 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15906538 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:15906538 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:15906538 | lifeskim:mentions | umls-concept:C0030186 | lld:lifeskim |
| pubmed-article:15906538 | lifeskim:mentions | umls-concept:C0031740 | lld:lifeskim |
| pubmed-article:15906538 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:15906538 | pubmed:dateCreated | 2005-5-23 | lld:pubmed |
| pubmed-article:15906538 | pubmed:abstractText | Photodynamic therapy (PDT), which employs a combination of a tumor-localizing photosensitizer and visible light, has been used in the treatment of extramammary Paget's disease (EMPD). Two patients with EMPD were treated with PDT using 5-aminolevulinic acid (ALA). Histologically, in both cases, Paget's cells were present within the epidermis. Case 1 was a 92-year-old male who underwent total extirpation for treatment of EMPD. Two topical ALA-PDT treatments were applied to parts of the lesions at a total dose of 200J/cm2. Case 2 was a 73-year-old female, whose lesions in the right labia majora were treated with 3 topical ALA-PDT sessions at a total dose of 300 J/cm2. Clinical findings after the irradiation showed improvement in both patients, and elimination of tumor cells in the epidermis was confirmed histologically. Case 1 had no recurrence in the irradiation field at three months after PDT. Case 2 had a recurrence only in the periphery parts of the lesions at two months after PDT, but the periphery lesions remitted with two more PDT treatments. Topical ALA-PDT is an effective treatment for EMPD with tumor cells within the epidermis. It is noninvasive and achieves a cosmetically excellent outcome, especially in elderly patients and those in poor general condition. | lld:pubmed |
| pubmed-article:15906538 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15906538 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15906538 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15906538 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15906538 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15906538 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15906538 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:15906538 | pubmed:issn | 0385-2407 | lld:pubmed |
| pubmed-article:15906538 | pubmed:author | pubmed-author:KobayashiMiyu... | lld:pubmed |
| pubmed-article:15906538 | pubmed:author | pubmed-author:WatanabeDaisu... | lld:pubmed |
| pubmed-article:15906538 | pubmed:author | pubmed-author:TamadaYasuhik... | lld:pubmed |
| pubmed-article:15906538 | pubmed:author | pubmed-author:MatsumotoYosh... | lld:pubmed |
| pubmed-article:15906538 | pubmed:author | pubmed-author:KondoChiharuC | lld:pubmed |
| pubmed-article:15906538 | pubmed:author | pubmed-author:MikasaKiyomiK | lld:pubmed |
| pubmed-article:15906538 | pubmed:author | pubmed-author:NakasekoHiron... | lld:pubmed |
| pubmed-article:15906538 | pubmed:author | pubmed-author:YokooKazuhisa... | lld:pubmed |
| pubmed-article:15906538 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15906538 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:15906538 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15906538 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15906538 | pubmed:pagination | 97-101 | lld:pubmed |
| pubmed-article:15906538 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:meshHeading | pubmed-meshheading:15906538... | lld:pubmed |
| pubmed-article:15906538 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15906538 | pubmed:articleTitle | 5-Aminolevulinic acid-based photodynamic therapy for the treatment of two patients with extramammary Paget's disease. | lld:pubmed |
| pubmed-article:15906538 | pubmed:affiliation | Department of Dermatology, Aichi Medical University School of Medicine, Nagakute, Aichi-gun, Aichi 480-1195, Japan. | lld:pubmed |
| pubmed-article:15906538 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15906538 | pubmed:publicationType | Case Reports | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15906538 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15906538 | lld:pubmed |
