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pubmed-article:15891334pubmed:abstractTextKetamine, an intravenous anesthetic agent, can modulate vascular tone. Nitric oxide (NO), constitutively produced in endothelial cells, contributes to vasoregulation. In this study, we attempted to evaluate the effects of ketamine on NO biosynthesis in human umbilical vein endothelial cells and its possible mechanism.lld:pubmed
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pubmed-article:15891334pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:15891334pubmed:articleTitleKetamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells by down-regulating endothelial nitric oxide synthase expression and intracellular calcium levels.lld:pubmed
pubmed-article:15891334pubmed:affiliationGraduate Institute of Medical Sciences, Department of Anesthesiology, Wan-Fang Hospital, College of Medicine, Taipei Medical University, Taipei, Taiwan.lld:pubmed
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