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pubmed-article:15819995pubmed:abstractTextIt has been postulated that genetic predisposition may influence the susceptibility to SARS-coronavirus infection and disease outcomes. A recent study has suggested that the deletion allele (D allele) of the angiotensin converting enzyme (ACE) gene is associated with hypoxemia in SARS patients. Moreover, the ACE D allele has been shown to be more prevalent in patients suffering from adult respiratory distress syndrome (ARDS) in a previous study. Thus, we have investigated the association between ACE insertion/deletion (I/D) polymorphism and the progression to ARDS or requirement of intensive care in SARS patients.lld:pubmed
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pubmed-article:15819995pubmed:articleTitleAbsence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study.lld:pubmed
pubmed-article:15819995pubmed:affiliationThe Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong. allen@cuhk.edu.hklld:pubmed
pubmed-article:15819995pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15819995pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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