| pubmed-article:15803146 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15803146 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:15803146 | lifeskim:mentions | umls-concept:C1655731 | lld:lifeskim |
| pubmed-article:15803146 | lifeskim:mentions | umls-concept:C0085536 | lld:lifeskim |
| pubmed-article:15803146 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:15803146 | lifeskim:mentions | umls-concept:C0920425 | lld:lifeskim |
| pubmed-article:15803146 | lifeskim:mentions | umls-concept:C1513403 | lld:lifeskim |
| pubmed-article:15803146 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:15803146 | pubmed:dateCreated | 2005-7-18 | lld:pubmed |
| pubmed-article:15803146 | pubmed:abstractText | Promoter methylation-mediated silencing is a hallmark of many established tumor suppressor genes. This review focuses on the methylation and suppression of a receptor-type tyrosine phosphatase gene, PTPRO, in a variety of solid and liquid tumors. In addition, PTPRO exhibits many other characteristics of a bona fide tumor suppressor. Reactivation of genes silenced by methylation using inhibitors of DNA methyltransferases and histone deacetylases, and the potential application of PTPRO as a molecular target for cancer therapy have been discussed. | lld:pubmed |
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| pubmed-article:15803146 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15803146 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15803146 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15803146 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15803146 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15803146 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:15803146 | pubmed:issn | 0929-1903 | lld:pubmed |
| pubmed-article:15803146 | pubmed:author | pubmed-author:JacobSamson... | lld:pubmed |
| pubmed-article:15803146 | pubmed:author | pubmed-author:MotiwalaTasne... | lld:pubmed |
| pubmed-article:15803146 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15803146 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:15803146 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15803146 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15803146 | pubmed:pagination | 665-72 | lld:pubmed |
| pubmed-article:15803146 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
| pubmed-article:15803146 | pubmed:meshHeading | pubmed-meshheading:15803146... | lld:pubmed |
| pubmed-article:15803146 | pubmed:meshHeading | pubmed-meshheading:15803146... | lld:pubmed |
