| pubmed-article:15738654 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15738654 | lifeskim:mentions | umls-concept:C0012917 | lld:lifeskim |
| pubmed-article:15738654 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
| pubmed-article:15738654 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
| pubmed-article:15738654 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:15738654 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:15738654 | pubmed:dateCreated | 2005-5-6 | lld:pubmed |
| pubmed-article:15738654 | pubmed:abstractText | The small DNA tumor viruses encode proteins that subvert many of the pivotal growth regulatory pathways within the cell to facilitate their own replication. The cell responds to viral infection/proteins by activating the p53 tumor suppressor pathway. Activation of p53 could impair a productive viral infection at many levels, including the inhibition of viral DNA replication and/or the premature death of infected cells. Therefore, DNA viruses encode proteins that inactivate the p53 tumor suppressor pathway. Understanding how DNA viral proteins activate/inactivate the p53 pathway has provided invaluable insights into tumorigenesis. Recent studies with polyoma virus have identified a viral protein (PyST) that inhibits ARF-mediated activation of p53, and revealed a novel role for PP2A in the regulation of the ARF-p53 tumor suppressor pathway. | lld:pubmed |
| pubmed-article:15738654 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15738654 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15738654 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15738654 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15738654 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15738654 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15738654 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15738654 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15738654 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15738654 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:15738654 | pubmed:issn | 1551-4005 | lld:pubmed |
| pubmed-article:15738654 | pubmed:author | pubmed-author:FriedMikeM | lld:pubmed |
| pubmed-article:15738654 | pubmed:author | pubmed-author:O'SheaClodagh... | lld:pubmed |
| pubmed-article:15738654 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:15738654 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:15738654 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15738654 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15738654 | pubmed:pagination | 449-52 | lld:pubmed |
| pubmed-article:15738654 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:15738654 | pubmed:meshHeading | pubmed-meshheading:15738654... | lld:pubmed |
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| pubmed-article:15738654 | pubmed:meshHeading | pubmed-meshheading:15738654... | lld:pubmed |
| pubmed-article:15738654 | pubmed:meshHeading | pubmed-meshheading:15738654... | lld:pubmed |
| pubmed-article:15738654 | pubmed:meshHeading | pubmed-meshheading:15738654... | lld:pubmed |
| pubmed-article:15738654 | pubmed:meshHeading | pubmed-meshheading:15738654... | lld:pubmed |
| pubmed-article:15738654 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15738654 | pubmed:articleTitle | Modulation of the ARF-p53 pathway by the small DNA tumor viruses. | lld:pubmed |
| pubmed-article:15738654 | pubmed:affiliation | UCSF Cancer Research Institute, San Francisco, California 94115, USA. | lld:pubmed |
| pubmed-article:15738654 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15738654 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15738654 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:15738654 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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