| pubmed-article:15725477 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15725477 | lifeskim:mentions | umls-concept:C1517806 | lld:lifeskim |
| pubmed-article:15725477 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:15725477 | lifeskim:mentions | umls-concept:C0016026 | lld:lifeskim |
| pubmed-article:15725477 | lifeskim:mentions | umls-concept:C0380603 | lld:lifeskim |
| pubmed-article:15725477 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:15725477 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15725477 | pubmed:dateCreated | 2005-2-23 | lld:pubmed |
| pubmed-article:15725477 | pubmed:abstractText | Fibroblast growth factor-2 (FGF-2) is a growth and survival factor whose expression is elevated in many hematopoietic malignancies. A natural antisense RNA (FGF-AS) has been implicated in the posttranscriptional regulation of FGF-2 mRNA expression. We demonstrate for the first time that FGF sense and antisense RNAs are coordinately expressed and translated in hematopoietic cells and tissues. Cytokine stimulation of growth-arrested K562 cells elicited a rapid transient increase in FGF-AS mRNA expression followed by a slower but sustained increase in FGF-2 mRNA. This was accompanied by a marked increase in the expression and nuclear translocation of FGF-2 and the FGF-AS encoded protein, GFG/NUDT6. These findings suggest a role for both FGF-2 and GFG proteins in the cell survival and proliferation of lymphoid and myeloid tumor cells. | lld:pubmed |
| pubmed-article:15725477 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15725477 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15725477 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15725477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15725477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15725477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15725477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15725477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15725477 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15725477 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:15725477 | pubmed:issn | 0145-2126 | lld:pubmed |
| pubmed-article:15725477 | pubmed:author | pubmed-author:CassonAlan... | lld:pubmed |
| pubmed-article:15725477 | pubmed:author | pubmed-author:TooCatherine... | lld:pubmed |
| pubmed-article:15725477 | pubmed:author | pubmed-author:GeldenhuysLau... | lld:pubmed |
| pubmed-article:15725477 | pubmed:author | pubmed-author:OsmanMohammed... | lld:pubmed |
| pubmed-article:15725477 | pubmed:author | pubmed-author:Baguma-Nibash... | lld:pubmed |
| pubmed-article:15725477 | pubmed:author | pubmed-author:LiAudrey WAW | lld:pubmed |
| pubmed-article:15725477 | pubmed:author | pubmed-author:MurphyPaul... | lld:pubmed |
| pubmed-article:15725477 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15725477 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:15725477 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15725477 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15725477 | pubmed:pagination | 423-33 | lld:pubmed |
| pubmed-article:15725477 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:meshHeading | pubmed-meshheading:15725477... | lld:pubmed |
| pubmed-article:15725477 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15725477 | pubmed:articleTitle | Coexpression and regulation of the FGF-2 and FGF antisense genes in leukemic cells. | lld:pubmed |
| pubmed-article:15725477 | pubmed:affiliation | Department of Physiology and Biophysics, Faculty of Medicine, Dalhousie University, 5850 College Street, Halifax, Nova Scotia, Canada B3H 1X5. | lld:pubmed |
| pubmed-article:15725477 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15725477 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:2247 | entrezgene:pubmed | pubmed-article:15725477 | lld:entrezgene |
| entrez-gene:54250 | entrezgene:pubmed | pubmed-article:15725477 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15725477 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15725477 | lld:entrezgene |
| lhgdn:association:40470 | lhgdn:found_in | pubmed-article:15725477 | lld:lhgdn |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15725477 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15725477 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15725477 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15725477 | lld:pubmed |
