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pubmed-article:15723258pubmed:abstractTextThe microtubule-stabilizing agent patupilone (epothilone B, EPO906) and the tyrosine kinase inhibitor imatinib (STI571, Glivec) which primarily inhibits Bcr-Abl, PDGF and c-Kit tyrosine kinase receptors, were combined in vivo to determine if any interaction would occur with respect to antitumour effect and tolerability using rat C6 glioma xenografted into nude mice.lld:pubmed
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pubmed-article:15723258pubmed:articleTitlePatupilone (epothilone B, EPO906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma.lld:pubmed
pubmed-article:15723258pubmed:affiliationOncology Research, Novartis Institutes for BioMedical Research, Basel, Switzerland.lld:pubmed
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