| pubmed-article:15686937 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C0030274 | lld:lifeskim |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C0003765 | lld:lifeskim |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C0041980 | lld:lifeskim |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C1256369 | lld:lifeskim |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C1709915 | lld:lifeskim |
| pubmed-article:15686937 | lifeskim:mentions | umls-concept:C0205224 | lld:lifeskim |
| pubmed-article:15686937 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15686937 | pubmed:dateCreated | 2005-2-2 | lld:pubmed |
| pubmed-article:15686937 | pubmed:abstractText | Uric acid (1a) suppresses basal insulin release in isolated rat pancreatic islets and inhibition of glucose-stimulated insulin secretion (GSIS) occurs right at hyperuricaemic levels (0.4 mM). Conversely, 1 mM guanidinium urate (2a) was completely ineffective, strongly suggesting that binding to an essential arginine residue triggers the inhibitory effect. A specific recognition of 1a molecule at the crucial beta-cell receptor is probably involved in the blocking glucose signal transduction. | lld:pubmed |
| pubmed-article:15686937 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15686937 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15686937 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15686937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15686937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15686937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15686937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15686937 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15686937 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:15686937 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:15686937 | pubmed:author | pubmed-author:BertuzziFeder... | lld:pubmed |
| pubmed-article:15686937 | pubmed:author | pubmed-author:PojeNevenkaN | lld:pubmed |
| pubmed-article:15686937 | pubmed:author | pubmed-author:PojeMirkoM | lld:pubmed |
| pubmed-article:15686937 | pubmed:author | pubmed-author:Roci?BorisB | lld:pubmed |
| pubmed-article:15686937 | pubmed:author | pubmed-author:Vuci?-Lovrenc... | lld:pubmed |
| pubmed-article:15686937 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15686937 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:15686937 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:15686937 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15686937 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15686937 | pubmed:pagination | 1181-4 | lld:pubmed |
| pubmed-article:15686937 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:meshHeading | pubmed-meshheading:15686937... | lld:pubmed |
| pubmed-article:15686937 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15686937 | pubmed:articleTitle | Uric acid may inhibit glucose-induced insulin secretion via binding to an essential arginine residue in rat pancreatic beta-cells. | lld:pubmed |
| pubmed-article:15686937 | pubmed:affiliation | University Clinic Vuk Vrhovac, Medical Faculty, Dugi dol 4a, 10000 Zagreb, Croatia. | lld:pubmed |
| pubmed-article:15686937 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15686937 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:15686937 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15686937 | lld:chembl |
