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pubmed-article:15679715pubmed:abstractTextPatients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 therapy are a challenging population with significant unmet medical need. We determined the effect of omalizumab on clinically significant asthma exacerbations (requiring systemic corticosteroids) in the first omalizumab study to exclusively enrol patients from this difficult-to-treat patient population.lld:pubmed
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pubmed-article:15679715pubmed:affiliationHôpital Antoine Beclere, Clamart, France.lld:pubmed
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