| pubmed-article:15664656 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15664656 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:15664656 | lifeskim:mentions | umls-concept:C0162609 | lld:lifeskim |
| pubmed-article:15664656 | lifeskim:mentions | umls-concept:C1090444 | lld:lifeskim |
| pubmed-article:15664656 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:15664656 | pubmed:dateCreated | 2005-1-24 | lld:pubmed |
| pubmed-article:15664656 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15664656 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15664656 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15664656 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15664656 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15664656 | pubmed:abstractText | daf-7 is a key ligand in one of the three pathways that control dauer larva development in Caenorhabditis elegans. Given the similarities between dauer larvae of free-living nematodes and third stage infective larvae of animal parasitic nematodes, we hypothesised that daf-7 may be involved in the development of these infective larvae. To investigate this, we cloned daf-7 orthologues from Strongyloides ratti and Parastrongyloides trichosuri and analysed their RNA level by semi-quantitative RT-PCR during the S. ratti and P. trichosuri life cycles and in a range of in vitro and in vivo conditions. We found that, in both species, the RNA level of daf-7 was low in free-living stages but peaked in the infective L3 (iL3) stage with little or no expression in the parasitic stages. This contrasts with the daf-7 RNA level in C. elegans, which peaks in L1, decreases thereafter, and is absent in dauer larvae. The RNA level of daf-7 in infective larvae was reduced by larval penetration of host skin or development in the host, but not by a shift to the body temperature of the host. | lld:pubmed |
| pubmed-article:15664656 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15664656 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15664656 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15664656 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15664656 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15664656 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15664656 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15664656 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:15664656 | pubmed:issn | 0166-6851 | lld:pubmed |
| pubmed-article:15664656 | pubmed:author | pubmed-author:VineyMark EME | lld:pubmed |
| pubmed-article:15664656 | pubmed:author | pubmed-author:ThompsonFiona... | lld:pubmed |
| pubmed-article:15664656 | pubmed:author | pubmed-author:GrantWarwick... | lld:pubmed |
| pubmed-article:15664656 | pubmed:author | pubmed-author:CrookMattM | lld:pubmed |
| pubmed-article:15664656 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15664656 | pubmed:volume | 139 | lld:pubmed |
| pubmed-article:15664656 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15664656 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15664656 | pubmed:pagination | 213-23 | lld:pubmed |
| pubmed-article:15664656 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:15664656 | pubmed:meshHeading | pubmed-meshheading:15664656... | lld:pubmed |
| pubmed-article:15664656 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15664656 | pubmed:articleTitle | daf-7 and the development of Strongyloides ratti and Parastrongyloides trichosuri. | lld:pubmed |
| pubmed-article:15664656 | pubmed:affiliation | School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, UK. | lld:pubmed |
| pubmed-article:15664656 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15664656 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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