| pubmed-article:15655776 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15655776 | lifeskim:mentions | umls-concept:C0149678 | lld:lifeskim |
| pubmed-article:15655776 | lifeskim:mentions | umls-concept:C0205177 | lld:lifeskim |
| pubmed-article:15655776 | lifeskim:mentions | umls-concept:C2709199 | lld:lifeskim |
| pubmed-article:15655776 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:15655776 | lifeskim:mentions | umls-concept:C0205191 | lld:lifeskim |
| pubmed-article:15655776 | lifeskim:mentions | umls-concept:C1705242 | lld:lifeskim |
| pubmed-article:15655776 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15655776 | pubmed:dateCreated | 2005-1-18 | lld:pubmed |
| pubmed-article:15655776 | pubmed:abstractText | Infections of T cells and natural killer (NK) cells play a central role in the pathogenesis of chronic active Epstein-Barr virus (CAEBV) infection. To characterize the virologic and cytokine profiles of T cell-type and NK cell-type infection, 39 patients with CAEBV infection were analyzed. Patients with T cell-type infection had higher titers of immunoglobulin G against early and late EBV antigens, suggesting lytic cycle infection. However, the pattern of EBV gene expression was latency type II; BZLF1, which is a hallmark of lytic cycle infection, could not be detected in any patients, regardless of infection type. Patients with CAEBV infection had high concentrations of proinflammatory, T helper cell type 1, and anti-inflammatory cytokines. The cytokine profile in patients with NK cell-type infection was similar to that in patients with T cell-type infection, but the concentration of IL-13 was high in patients with NK cell-type infection. These findings should help to clarify the pathogenesis of CAEBV infection and facilitate the development of more-effective treatments. | lld:pubmed |
| pubmed-article:15655776 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15655776 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15655776 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:15655776 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15655776 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15655776 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15655776 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15655776 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15655776 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15655776 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:15655776 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:KimuraHiroshi... | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:NagasakaTetsu... | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:KojimaSeijiS | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:HoshinoYoY | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:KuzushimaKiyo... | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:HaraShinyaS | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:MorishimaTsun... | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:KawadaJun-Ich... | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:SugayaNaomiN | lld:pubmed |
| pubmed-article:15655776 | pubmed:author | pubmed-author:ShibataYukiko... | lld:pubmed |
| pubmed-article:15655776 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15655776 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:15655776 | pubmed:volume | 191 | lld:pubmed |
| pubmed-article:15655776 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15655776 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15655776 | pubmed:pagination | 531-9 | lld:pubmed |
| pubmed-article:15655776 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:15655776 | pubmed:meshHeading | pubmed-meshheading:15655776... | lld:pubmed |
| pubmed-article:15655776 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15655776 | pubmed:articleTitle | Differences between T cell-type and natural killer cell-type chronic active Epstein-Barr virus infection. | lld:pubmed |
| pubmed-article:15655776 | pubmed:affiliation | Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan. hkimura@med.nagoya-u.ac.jp | lld:pubmed |
| pubmed-article:15655776 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15655776 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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