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pubmed-article:15653659pubmed:abstractTextIn patients with progressive metastatic (or recurrent) differentiated thyroid carcinoma (DTC) who do not respond to radioiodine therapy or do not show uptake on radioiodine scintigraphy, treatment options are few. Because these tumors may express somatostatin receptors, peptide receptor radionuclide therapy might be effective. We evaluated the therapeutic efficacy of the radiolabeled somatostatin analog (177)Lu-1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid(0) (DOTA), Tyr(3)-octreotate ((177)Lu-DOTATATE) in patients with DTC. The uptake of radioactivity in tumors was also studied in relation to treatment outcome.lld:pubmed
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pubmed-article:15653659pubmed:volume46 Suppl 1lld:pubmed
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pubmed-article:15653659pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:15653659pubmed:year2005lld:pubmed
pubmed-article:15653659pubmed:articleTitlePeptide receptor radionuclide therapy for non-radioiodine-avid differentiated thyroid carcinoma.lld:pubmed
pubmed-article:15653659pubmed:affiliationDepartment of Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands. j.teunissen@erasmusmc.nllld:pubmed
pubmed-article:15653659pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15653659pubmed:publicationTypeClinical Triallld:pubmed