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pubmed-article:15637325pubmed:abstractTextPrevious studies have suggested that delayed release of hemoglobin degradation products, particularly iron, is involved in intracerebral hemorrhage (ICH)-induced brain injury. However, a recent study found evidence of iron-induced brain injury soon after ICH. This study, therefore, examined whether another iron-containing component of blood, holo-transferrin (holo-Tf), might also induce brain injury either alone or in combination with thrombin, another factor involved in early ICH-induced brain injury.lld:pubmed
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pubmed-article:15637325pubmed:articleTitleHolo-transferrin and thrombin can interact to cause brain damage.lld:pubmed
pubmed-article:15637325pubmed:affiliationDepartment of Neurosurgery, University of Michigan, Ann Arbor, Michigan 48109-0532, USA.lld:pubmed
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