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pubmed-article:15625653pubmed:abstractTextTransmural inflammation, a distinguishing feature of Crohn's disease (CD), cannot be assessed by conventional colonoscopy with mucosal biopsy. Our previous ex vivo study of histology-correlated optical coherence tomography (OCT) imaging on colectomy specimens of CD and ulcerative colitis (UC) showed that disruption of the layered structure of colon wall on OCT is an accurate marker for transmural inflammation of CD. We performed an in vivo colonoscopic OCT in patients with a clinical diagnosis of CD or UC using the previously established, histology-correlated OCT imaging criterion.lld:pubmed
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pubmed-article:15625653pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:15625653pubmed:articleTitleIn vivo colonoscopic optical coherence tomography for transmural inflammation in inflammatory bowel disease.lld:pubmed
pubmed-article:15625653pubmed:affiliationDepartment of Gastroenterology/Hepatology, the Cleveland Clinic Foundation, Ohio 44195, USA. shenb@ccf.orglld:pubmed
pubmed-article:15625653pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15625653pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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