Normal gating of CFTR requires ATP binding to both nucleotide-binding domains and hydrolysis at the second nucleotide-binding domain.

Source:http://linkedlifedata.com/resource/pubmed/id/15623556

Proc. Natl. Acad. Sci. U.S.A. 2005 Jan 11 102 2 455-60

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PMID
15623556