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pubmed-article:15613909pubmed:abstractTextA patient with stage IV non-Hodgkin's lymphoma and chronic hepatitis who was treated with chemotherapy and rituximab developed fatal reactivation of hepatitis B. High viral load titers of hepatitis B DNA were demonstrated. DNA sequencing analysis revealed the presence of the precore mutant strain. Hepatitis B reactivation in patients receiving rituxmab-based chemotherapy is reviewed and the role of precore mutant virus strains resulting in fatal complications is discussed.lld:pubmed
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pubmed-article:15613909pubmed:authorpubmed-author:ZellJason AJAlld:pubmed
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pubmed-article:15613909pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:15613909pubmed:articleTitlePrecore mutant hepatitis B reactivation after treatment with CHOP-rituximab.lld:pubmed
pubmed-article:15613909pubmed:affiliationDivision of Hematology/Oncology, Department of Medicine, College of Medicine, University of California Irvine, Irvine, CA, USA. jzell@uci.edulld:pubmed
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