| pubmed-article:15596857 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15596857 | lifeskim:mentions | umls-concept:C0042776 | lld:lifeskim |
| pubmed-article:15596857 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:15596857 | lifeskim:mentions | umls-concept:C0007585 | lld:lifeskim |
| pubmed-article:15596857 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:15596857 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:15596857 | pubmed:dateCreated | 2004-12-14 | lld:pubmed |
| pubmed-article:15596857 | pubmed:abstractText | To override the diffusion-limited adsorption step of viral infection, we magnetically synchronized cell attachment. Human immunodeficiency virus type 1-based lentivirus preparations were rendered magnetically reactive by association with magnetite nanoparticles, 50 nm in diameter. Application of a magnetic field resulted in immediate redistribution of the viral inoculum to the cell-associated state and completion of the productive adsorption process within 1 min. Independent of adsorption time, viral concentration, and diffusion rate, infection subsequently progressed by the receptor-mediated entry mechanism. Synchronization of this rate-limiting step of infection may now be applied to analyze isolated events in the viral replication sequence. | lld:pubmed |
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| pubmed-article:15596857 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15596857 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15596857 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:15596857 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15596857 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:15596857 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:15596857 | pubmed:author | pubmed-author:SteinerIsrael... | lld:pubmed |
| pubmed-article:15596857 | pubmed:author | pubmed-author:PanetAmosA | lld:pubmed |
| pubmed-article:15596857 | pubmed:author | pubmed-author:HaimHillelH | lld:pubmed |
| pubmed-article:15596857 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15596857 | pubmed:volume | 79 | lld:pubmed |
| pubmed-article:15596857 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15596857 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15596857 | pubmed:pagination | 622-5 | lld:pubmed |
| pubmed-article:15596857 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:15596857 | pubmed:meshHeading | pubmed-meshheading:15596857... | lld:pubmed |
| pubmed-article:15596857 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15596857 | pubmed:articleTitle | Synchronized infection of cell cultures by magnetically controlled virus. | lld:pubmed |
| pubmed-article:15596857 | pubmed:affiliation | Department of Virology, Hadassah Medical School, The Hebrew University, Jerusalem, Israel. hhaim@md.huji.ac.il | lld:pubmed |
| pubmed-article:15596857 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15596857 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:15596857 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
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