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pubmed-article:15596677pubmed:abstractTextThe increased expression of matrix metalloproteinases (MMPs) is considered to be a key factor in the development of COPD. Net MMP activity represents a tightly regulated process, which is not addressed by conventional investigation methods such as messenger RNA or protein expression. Yet, quantitative data on MMP activity in the airways of COPD patients are lacking.lld:pubmed
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pubmed-article:15596677pubmed:articleTitleIncreased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD.lld:pubmed
pubmed-article:15596677pubmed:affiliationDepartment of Respiratory Medicine, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, the Netherlands. j.vernooy@pul.unimaas.nllld:pubmed
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