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pubmed-article:15576635pubmed:abstractTextProstaglandin E synthases (PGESs) are being explored as antiinflammatory drug targets as alternatives to cyclooxygenase (COX)-2. Located downstream of the cyclooxygenases, PGESs catalyze PGE(2) formation, and deletion of microsomal (m)-PGES-1 abrogates inflammation. We sought to characterize the developmental expression of COX and PGES in zebrafish.lld:pubmed
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pubmed-article:15576635pubmed:articleTitleProstaglandin E synthases in zebrafish.lld:pubmed
pubmed-article:15576635pubmed:affiliationInstitute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia 19104-6084, USA.lld:pubmed
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