| pubmed-article:1557031 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0033618 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0012854 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0038952 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C1442161 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0220905 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:1557031 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:1557031 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:1557031 | pubmed:dateCreated | 1992-5-6 | lld:pubmed |
| pubmed-article:1557031 | pubmed:abstractText | In the yeast Saccharomyces cerevisiae the RAD2 gene is absolutely required for damage-specific incision of DNA during nucleotide excision repair and is inducible by DNA-damaging agents. In the present study we correlated sensitivity to killing by DNA-damaging agents with the deletion of previously defined specific promoter elements. Deletion of the element DRE2 increased the UV sensitivity of cells in both the G1/early S and S/G2 phases of the cell cycle as well as in stationary phase. On the other hand, increased UV sensitivity associated with deletion of the sequence-related element DRE1 was restricted to cells irradiated in G1/S. Specific binding of protein(s) to the promoter elements DRE1 and DRE2 was observed under non-inducing conditions using gel retardation assays. Exposure of cells to DNA-damaging agents resulted in increased protein binding that was dependent on de novo protein synthesis. | lld:pubmed |
| pubmed-article:1557031 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1557031 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1557031 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1557031 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1557031 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1557031 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1557031 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1557031 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:1557031 | pubmed:issn | 0026-8925 | lld:pubmed |
| pubmed-article:1557031 | pubmed:author | pubmed-author:SiedeWW | lld:pubmed |
| pubmed-article:1557031 | pubmed:author | pubmed-author:FriedbergE... | lld:pubmed |
| pubmed-article:1557031 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1557031 | pubmed:volume | 232 | lld:pubmed |
| pubmed-article:1557031 | pubmed:geneSymbol | RAD2 | lld:pubmed |
| pubmed-article:1557031 | pubmed:geneSymbol | DRE2 | lld:pubmed |
| pubmed-article:1557031 | pubmed:geneSymbol | DRE1 | lld:pubmed |
| pubmed-article:1557031 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1557031 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1557031 | pubmed:pagination | 247-56 | lld:pubmed |
| pubmed-article:1557031 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
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| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:meshHeading | pubmed-meshheading:1557031-... | lld:pubmed |
| pubmed-article:1557031 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1557031 | pubmed:articleTitle | Regulation of the yeast RAD2 gene: DNA damage-dependent induction correlates with protein binding to regulatory sequences and their deletion influences survival. | lld:pubmed |
| pubmed-article:1557031 | pubmed:affiliation | Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235. | lld:pubmed |
| pubmed-article:1557031 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1557031 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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