| pubmed-article:15542373 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15542373 | lifeskim:mentions | umls-concept:C0282580 | lld:lifeskim |
| pubmed-article:15542373 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
| pubmed-article:15542373 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15542373 | pubmed:dateCreated | 2004-11-15 | lld:pubmed |
| pubmed-article:15542373 | pubmed:abstractText | TEPITOPE is a prediction model that has been successfully applied to the in silico identification of T cell epitopes in the context of oncology, allergy, infectious diseases, and autoimmune diseases. Like most epitope prediction models, TEPITOPE's underlying algorithm is based on the prediction of HLA-II peptide binding, which constitutes a major bottleneck in the natural selection of epitopes. An important step in the design of subunit vaccines is the identification of promiscuous HLA-II ligands in sets of disease-specific gene products. TEPITOPE's user interface enables the systematic prediction of promiscuous peptide ligands for a broad range of HLA-binding specificity. We show how to apply the TEPITOPE prediction model to identify T cell epitopes, and provide both a road map and examples of its successful application. | lld:pubmed |
| pubmed-article:15542373 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15542373 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15542373 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15542373 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15542373 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15542373 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15542373 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15542373 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15542373 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:15542373 | pubmed:issn | 1046-2023 | lld:pubmed |
| pubmed-article:15542373 | pubmed:author | pubmed-author:HammerJuergen... | lld:pubmed |
| pubmed-article:15542373 | pubmed:author | pubmed-author:BianHongjinH | lld:pubmed |
| pubmed-article:15542373 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15542373 | pubmed:volume | 34 | lld:pubmed |
| pubmed-article:15542373 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15542373 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15542373 | pubmed:pagination | 468-75 | lld:pubmed |
| pubmed-article:15542373 | pubmed:meshHeading | pubmed-meshheading:15542373... | lld:pubmed |
| pubmed-article:15542373 | pubmed:meshHeading | pubmed-meshheading:15542373... | lld:pubmed |
| pubmed-article:15542373 | pubmed:meshHeading | pubmed-meshheading:15542373... | lld:pubmed |
| pubmed-article:15542373 | pubmed:meshHeading | pubmed-meshheading:15542373... | lld:pubmed |
| pubmed-article:15542373 | pubmed:meshHeading | pubmed-meshheading:15542373... | lld:pubmed |
| pubmed-article:15542373 | pubmed:meshHeading | pubmed-meshheading:15542373... | lld:pubmed |
| pubmed-article:15542373 | pubmed:meshHeading | pubmed-meshheading:15542373... | lld:pubmed |
| pubmed-article:15542373 | pubmed:meshHeading | pubmed-meshheading:15542373... | lld:pubmed |
| pubmed-article:15542373 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15542373 | pubmed:articleTitle | Discovery of promiscuous HLA-II-restricted T cell epitopes with TEPITOPE. | lld:pubmed |
| pubmed-article:15542373 | pubmed:affiliation | Section of Bioinformatics, Genetics and Genomics, Hoffmann-La Roche Inc., Nutley, New Jersey, USA. | lld:pubmed |
| pubmed-article:15542373 | pubmed:publicationType | Journal Article | lld:pubmed |
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