| pubmed-article:15522127 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C0001349 | lld:lifeskim |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C0023401 | lld:lifeskim |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C0022702 | lld:lifeskim |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C1265611 | lld:lifeskim |
| pubmed-article:15522127 | lifeskim:mentions | umls-concept:C0332306 | lld:lifeskim |
| pubmed-article:15522127 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15522127 | pubmed:dateCreated | 2004-11-3 | lld:pubmed |
| pubmed-article:15522127 | pubmed:abstractText | The present study compared leucine kinetics and acute-phase-protein concentrations in three groups of marasmic, acutely infected Malawian children fed one of three isoenergetic diets. These were: an enhanced-protein-quality diet (egg-white+tryptophan, providing 1.2 g protein/kg per d; n 14); an increased-protein-content diet (egg-white+tryptophan, providing 1.8 g protein/kg per d; n 14); a standard-protein diet (1.2 g milk protein/kg per d; n 25). The hypotheses tested were that children receiving a diet with more protein would have greater rates of non-oxidative leucine disposal and that children receiving an isonitrogenous diet with a higher protein quality would have lower rates of leucine oxidation. The children were studied after 24 h of therapy using standard [(13)C]leucine stable-isotope tracer techniques. The children receiving the higher-protein-content diet had greater leucine kinetic rates than those receiving the standard-protein-content diet; non-oxidative leucine disposal was 170 (sd 52) v. 122 (sd 30) mumol leucine/kg per h (P<0.01). Leucine oxidation was less in the children receiving the enhanced-protein-quality diet than in those receiving the standard-protein-quality diet; 34 (sd 12) v. 45 (sd 13) mumol leucine/kg per h (P<0.05). The children receiving the high-protein-content diet increased their serum concentration for five of six acute-phase proteins 24 h after starting therapy, while those receiving the standard-protein-content diet did not. These data suggest that there was greater whole-body protein synthesis, and a more vigorous acute-phase response associated with the higher-protein-content diet. The clinical benefits associated with a higher protein intake in marasmic, acutely infected children need further study. | lld:pubmed |
| pubmed-article:15522127 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15522127 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15522127 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15522127 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15522127 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15522127 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15522127 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15522127 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15522127 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15522127 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15522127 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15522127 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:15522127 | pubmed:issn | 0007-1145 | lld:pubmed |
| pubmed-article:15522127 | pubmed:author | pubmed-author:SmithSS | lld:pubmed |
| pubmed-article:15522127 | pubmed:author | pubmed-author:HartC ACA | lld:pubmed |
| pubmed-article:15522127 | pubmed:author | pubmed-author:YarasheskiK... | lld:pubmed |
| pubmed-article:15522127 | pubmed:author | pubmed-author:ManaryM JMJ | lld:pubmed |
| pubmed-article:15522127 | pubmed:author | pubmed-author:AbramsE TET | lld:pubmed |
| pubmed-article:15522127 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15522127 | pubmed:volume | 92 | lld:pubmed |
| pubmed-article:15522127 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15522127 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15522127 | pubmed:pagination | 589-95 | lld:pubmed |
| pubmed-article:15522127 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:15522127 | pubmed:meshHeading | pubmed-meshheading:15522127... | lld:pubmed |
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| pubmed-article:15522127 | pubmed:meshHeading | pubmed-meshheading:15522127... | lld:pubmed |
| pubmed-article:15522127 | pubmed:meshHeading | pubmed-meshheading:15522127... | lld:pubmed |
| pubmed-article:15522127 | pubmed:meshHeading | pubmed-meshheading:15522127... | lld:pubmed |
| pubmed-article:15522127 | pubmed:meshHeading | pubmed-meshheading:15522127... | lld:pubmed |
| pubmed-article:15522127 | pubmed:meshHeading | pubmed-meshheading:15522127... | lld:pubmed |
| pubmed-article:15522127 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15522127 | pubmed:articleTitle | Protein quantity, not protein quality, accelerates whole-body leucine kinetics and the acute-phase response during acute infection in marasmic Malawian children. | lld:pubmed |
| pubmed-article:15522127 | pubmed:affiliation | College of Medicine, University of Malawi, Blantyre. manary@kids.wustl.edu | lld:pubmed |
| pubmed-article:15522127 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15522127 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
