pubmed-article:15518908 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15518908 | lifeskim:mentions | umls-concept:C1522449 | lld:lifeskim |
pubmed-article:15518908 | lifeskim:mentions | umls-concept:C1882880 | lld:lifeskim |
pubmed-article:15518908 | lifeskim:mentions | umls-concept:C0904504 | lld:lifeskim |
pubmed-article:15518908 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:15518908 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:15518908 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:15518908 | pubmed:issue | 1-3 | lld:pubmed |
pubmed-article:15518908 | pubmed:dateCreated | 2004-11-2 | lld:pubmed |
pubmed-article:15518908 | pubmed:abstractText | In the present work, PAC1-R (G-protein-coupled receptor specific for PACAP) was detected on cells in the normal thymus. Immunohistochemically PAC1-R was expressed strongly in stromal cells of the thymic medulla. Positive cells were also observed in the thymus of fetal and old adult rats. After 8 Gy irradiation to 9-week-old rats, PAC1-R expressions in the thymus decreased and almost recovered by day 21. The expression of PAC1-R mRNA was weak in the thymus and decreased further after irradiation. The expression almost recovered by day 28. Hip and hip/hop variants, which were not expressed in the normal thymus, were expressed in the thymus on days 3, 5 and 21 after irradiation. The expressions of IL-6 and IL-10 tended to increase initially after irradiation then decreased. Histologically, the thymic structures were destroyed on day 3 after irradiation and the thymus almost recovered by day 21. Thus PACAP is thought to be one of the important factors for cross-talk between cells involved in thymic regeneration. | lld:pubmed |
pubmed-article:15518908 | pubmed:language | eng | lld:pubmed |
pubmed-article:15518908 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15518908 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:15518908 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15518908 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15518908 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15518908 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15518908 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15518908 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15518908 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15518908 | pubmed:month | Dec | lld:pubmed |
pubmed-article:15518908 | pubmed:issn | 0167-0115 | lld:pubmed |
pubmed-article:15518908 | pubmed:author | pubmed-author:FunahashiHisa... | lld:pubmed |
pubmed-article:15518908 | pubmed:author | pubmed-author:ShiodaSeijiS | lld:pubmed |
pubmed-article:15518908 | pubmed:author | pubmed-author:MizutaniNorik... | lld:pubmed |
pubmed-article:15518908 | pubmed:author | pubmed-author:TokudaNobukoN | lld:pubmed |
pubmed-article:15518908 | pubmed:author | pubmed-author:SawadaTomooT | lld:pubmed |
pubmed-article:15518908 | pubmed:author | pubmed-author:FukumotoTetsu... | lld:pubmed |
pubmed-article:15518908 | pubmed:author | pubmed-author:YasuhiroAdach... | lld:pubmed |
pubmed-article:15518908 | pubmed:author | pubmed-author:HamasakiKeiko... | lld:pubmed |
pubmed-article:15518908 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15518908 | pubmed:day | 15 | lld:pubmed |
pubmed-article:15518908 | pubmed:volume | 123 | lld:pubmed |
pubmed-article:15518908 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15518908 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:15518908 | pubmed:pagination | 167-72 | lld:pubmed |
pubmed-article:15518908 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
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pubmed-article:15518908 | pubmed:year | 2004 | lld:pubmed |
pubmed-article:15518908 | pubmed:articleTitle | Expression of PAC1 receptor in rat thymus after irradiation. | lld:pubmed |
pubmed-article:15518908 | pubmed:affiliation | Department of Human Science, Yamaguchi University School of Medicine, Ube 755-8505, Japan. toku@yamaguchi-u.ac.jp | lld:pubmed |
pubmed-article:15518908 | pubmed:publicationType | Journal Article | lld:pubmed |