| pubmed-article:15512862 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15512862 | lifeskim:mentions | umls-concept:C0598958 | lld:lifeskim |
| pubmed-article:15512862 | lifeskim:mentions | umls-concept:C1513403 | lld:lifeskim |
| pubmed-article:15512862 | pubmed:dateCreated | 2004-10-29 | lld:pubmed |
| pubmed-article:15512862 | pubmed:abstractText | Amyotrophic lateral sclerosis (ALS) is a fatal paralytic neurodegenerative disorder. Experimental models of ALS such as the transgenic rodents expressing mutant superoxide dimutase-1 are playing a pivotal role in our understanding of ALS pathogenesis, and in our testing of new therapeutic interventions aimed at protecting against neurodegeneration. Apoptosis has emerged as a significant pathogenic factor in several neurodegenerative diseases, including ALS. Constructed of multiple interacting molecules, the apoptosis machinery offers a host of attractive targets for pharmacological and genetic interventions to be tested in experimental models of ALS. Information generated by these pre-clinical studies holds the promise to provide sound scientific basis for the development of effective neuroprotective therapies for ALS. | lld:pubmed |
| pubmed-article:15512862 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15512862 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15512862 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15512862 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15512862 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:15512862 | pubmed:issn | 1466-0822 | lld:pubmed |
| pubmed-article:15512862 | pubmed:author | pubmed-author:PrzedborskiSe... | lld:pubmed |
| pubmed-article:15512862 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15512862 | pubmed:volume | 5 Suppl 1 | lld:pubmed |
| pubmed-article:15512862 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15512862 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15512862 | pubmed:pagination | 14-8 | lld:pubmed |
| pubmed-article:15512862 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:15512862 | pubmed:meshHeading | pubmed-meshheading:15512862... | lld:pubmed |
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| pubmed-article:15512862 | pubmed:meshHeading | pubmed-meshheading:15512862... | lld:pubmed |
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| pubmed-article:15512862 | pubmed:meshHeading | pubmed-meshheading:15512862... | lld:pubmed |
| pubmed-article:15512862 | pubmed:meshHeading | pubmed-meshheading:15512862... | lld:pubmed |
| pubmed-article:15512862 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15512862 | pubmed:articleTitle | Molecular targets for neuroprotection. | lld:pubmed |
| pubmed-article:15512862 | pubmed:affiliation | Departments of Neurology and Pathology, and the Center for Neurobiology and Behavior, Columbia University, New York, NY 10032, USA. SP30@columbia.edu | lld:pubmed |
| pubmed-article:15512862 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15512862 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15512862 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:15512862 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:15512862 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
