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pubmed-article:15468102pubmed:dateCreated2004-12-23lld:pubmed
pubmed-article:15468102pubmed:abstractTextTo investigate the role desmin may play in muscular adaptation to exercise, we measured desmin protein content in the vastus lateralis muscle of seven untrained men in response to 8 weeks of high-intensity cycle training. Training involved 15-s sprints separated by rest for 5 min. Subjects began with four sprints twice per week, and progressed to six sprints three times per week. Peak power was measured before and after training with a 30-s maximal sprint test. Mean power during the first 15 s increased significantly after training (P < 0.05). Desmin and actin protein levels were determined by immunoblotting, from pretraining and posttraining muscle biopsies. Desmin protein levels were increased by 60% after training (P < 0.01), whereas actin protein levels did not change with training. We conclude that the cytoskeletal protein desmin increases in response to a high-tension, concentric-only load consequent to sprint training. Desmin appears to increase as the force generating capacity of the muscle increases. A reinforced desmin cytoskeleton may be necessary for increased force generation by the muscle.lld:pubmed
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pubmed-article:15468102pubmed:authorpubmed-author:ParcellAllen...lld:pubmed
pubmed-article:15468102pubmed:authorpubmed-author:Woolstenhulme...lld:pubmed
pubmed-article:15468102pubmed:authorpubmed-author:JutteLisa SLSlld:pubmed
pubmed-article:15468102pubmed:authorpubmed-author:DrummondMicah...lld:pubmed
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pubmed-article:15468102pubmed:volume31lld:pubmed
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pubmed-article:15468102pubmed:pagination20-4lld:pubmed
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pubmed-article:15468102pubmed:year2005lld:pubmed
pubmed-article:15468102pubmed:articleTitleDesmin increases with high-intensity concentric contractions in humans.lld:pubmed
pubmed-article:15468102pubmed:affiliationHuman Performance Research Center, 120-E Richards Building, Brigham Young University, Provo, Utah 84602, USA.lld:pubmed
pubmed-article:15468102pubmed:publicationTypeJournal Articlelld:pubmed
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