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pubmed-article:15458455pubmed:abstractTextFabry disease is an X-linked inherited disorder that is caused by excessive lysosomal globotriaosylceramide (CTH) storage due to a deficiency in alpha-galactosidase A (alpha-Gal A). Two recombinant enzyme preparations have been approved as treatment modality. We studied emergence and properties of alpha-Gal A antibodies in treated patients.lld:pubmed
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pubmed-article:15458455pubmed:articleTitleEnzyme therapy for Fabry disease: neutralizing antibodies toward agalsidase alpha and beta.lld:pubmed
pubmed-article:15458455pubmed:affiliationDepartment of Internal Medicine/Clinical Hematology, Academic Medical Center, Amsterdam, The Netherlands. G.E.Linthorst@amc.uva.nllld:pubmed
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