| pubmed-article:15390062 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15390062 | lifeskim:mentions | umls-concept:C0019202 | lld:lifeskim |
| pubmed-article:15390062 | lifeskim:mentions | umls-concept:C0234378 | lld:lifeskim |
| pubmed-article:15390062 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:15390062 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:15390062 | pubmed:dateCreated | 2004-11-3 | lld:pubmed |
| pubmed-article:15390062 | pubmed:abstractText | The following study included 5 Wilson's disease (WD) patients showing a right-sided postural forearm tremor (4-6 Hz) and addressed the question of whether the primary motor cortex (M1) is involved in tremor generation. Using a 122-channel whole-head neuromagnetometer and surface electromyogram (EMG), we investigated cerebromuscular coupling. Postural tremor was observed in a sustained 45-degree posture of the right-sided forearm. Data were analyzed using dynamic imaging of coherent sources (DICS), revealing cerebromuscular coupling between EMG and cerebral activity. Coherent sources were superimposed on individual high-resolution T1-weighted magnetic resonance images (MRI). Phase lags between EMG and cerebral areas showing strongest coherence were determined by means of a Hilbert transform of both signals. In all patients, postural tremor was associated with strong coherence between tremor EMG and activity in contralateral primary sensorimotor cortex (S1/M1) at tremor or double tremor frequency. Phase lag values between S1/M1 activity and EMG revealed efferent and afferent components in the corticomuscular coupling. Taken together, our results indicate that postural tremor in WD is mediated through a pathological oscillatory drive from the primary motor cortex. | lld:pubmed |
| pubmed-article:15390062 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15390062 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15390062 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15390062 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15390062 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:15390062 | pubmed:issn | 0885-3185 | lld:pubmed |
| pubmed-article:15390062 | pubmed:author | pubmed-author:TimmermannLar... | lld:pubmed |
| pubmed-article:15390062 | pubmed:author | pubmed-author:SchnitzlerAlf... | lld:pubmed |
| pubmed-article:15390062 | pubmed:author | pubmed-author:PollokBettina... | lld:pubmed |
| pubmed-article:15390062 | pubmed:author | pubmed-author:HefterHaraldH | lld:pubmed |
| pubmed-article:15390062 | pubmed:author | pubmed-author:GrossJoachimJ | lld:pubmed |
| pubmed-article:15390062 | pubmed:author | pubmed-author:ButzMarkusM | lld:pubmed |
| pubmed-article:15390062 | pubmed:author | pubmed-author:SüdmeyerMarti... | lld:pubmed |
| pubmed-article:15390062 | pubmed:author | pubmed-author:WojteckiLarsL | lld:pubmed |
| pubmed-article:15390062 | pubmed:copyrightInfo | 2004 Movement Disorder Society. | lld:pubmed |
| pubmed-article:15390062 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15390062 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:15390062 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15390062 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15390062 | pubmed:pagination | 1476-82 | lld:pubmed |
| pubmed-article:15390062 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:meshHeading | pubmed-meshheading:15390062... | lld:pubmed |
| pubmed-article:15390062 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15390062 | pubmed:articleTitle | Postural tremor in Wilson's disease: a magnetoencephalographic study. | lld:pubmed |
| pubmed-article:15390062 | pubmed:affiliation | Department of Neurology, Heinrich-Heine-University, Düsseldorf, Germany. | lld:pubmed |
| pubmed-article:15390062 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15390062 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
