| pubmed-article:15388697 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15388697 | lifeskim:mentions | umls-concept:C0004611 | lld:lifeskim |
| pubmed-article:15388697 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:15388697 | lifeskim:mentions | umls-concept:C1490590 | lld:lifeskim |
| pubmed-article:15388697 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
| pubmed-article:15388697 | lifeskim:mentions | umls-concept:C2239486 | lld:lifeskim |
| pubmed-article:15388697 | pubmed:issue | Pt 5 | lld:pubmed |
| pubmed-article:15388697 | pubmed:dateCreated | 2004-9-24 | lld:pubmed |
| pubmed-article:15388697 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15388697 | pubmed:abstractText | The diversity of mucin-degrading bacteria in the human intestine was investigated by combining culture and 16S rRNA-dependent approaches. A dominant bacterium, strain MucT, was isolated by dilution to extinction of faeces in anaerobic medium containing gastric mucin as the sole carbon and nitrogen source. A pure culture was obtained using the anaerobic soft agar technique. Strain MucT was a Gram-negative, strictly anaerobic, non-motile, non-spore-forming, oval-shaped bacterium that could grow singly and in pairs. When grown on mucin medium, cells produced a capsule and were found to aggregate. Strain MucT could grow on a limited number of sugars, including N-acetylglucosamine, N-acetylgalactosamine and glucose, but only when a protein source was provided and with a lower growth rate and final density than on mucin. The G + C content of DNA from strain MucT was 47.6 mol%. 16S rRNA gene sequence analysis revealed that the isolate was part of the division Verrucomicrobia. The closest described relative of strain MucT was Verrucomicrobium spinosum (92 % sequence similarity). Remarkably, the 16S rRNA gene sequence of strain MucT showed 99 % similarity to three uncultured colonic bacteria. According to the data obtained in this work, strain MucT represents a novel bacterium belonging to a new genus in subdivision 1 of the Verrucomicrobia; the name Akkermansia muciniphila gen. nov., sp. nov. is proposed; the type strain is MucT (= ATCC BAA-835T = CIP 107961T). | lld:pubmed |
| pubmed-article:15388697 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15388697 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15388697 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15388697 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15388697 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15388697 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:15388697 | pubmed:issn | 1466-5026 | lld:pubmed |
| pubmed-article:15388697 | pubmed:author | pubmed-author:VaughanElaine... | lld:pubmed |
| pubmed-article:15388697 | pubmed:author | pubmed-author:de... | lld:pubmed |
| pubmed-article:15388697 | pubmed:author | pubmed-author:PluggeCarolin... | lld:pubmed |
| pubmed-article:15388697 | pubmed:author | pubmed-author:DerrienMuriel... | lld:pubmed |
| pubmed-article:15388697 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15388697 | pubmed:volume | 54 | lld:pubmed |
| pubmed-article:15388697 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15388697 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15388697 | pubmed:pagination | 1469-76 | lld:pubmed |
| pubmed-article:15388697 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:15388697 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15388697 | pubmed:articleTitle | Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. | lld:pubmed |
| pubmed-article:15388697 | pubmed:affiliation | Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, 6703 CT Wageningen, The Netherlands. muriel.derrien@wur.nl | lld:pubmed |
| pubmed-article:15388697 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15388697 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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