| pubmed-article:15380233 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15380233 | lifeskim:mentions | umls-concept:C0083026 | lld:lifeskim |
| pubmed-article:15380233 | lifeskim:mentions | umls-concept:C0001128 | lld:lifeskim |
| pubmed-article:15380233 | lifeskim:mentions | umls-concept:C0243076 | lld:lifeskim |
| pubmed-article:15380233 | pubmed:issue | 20 | lld:pubmed |
| pubmed-article:15380233 | pubmed:dateCreated | 2004-9-21 | lld:pubmed |
| pubmed-article:15380233 | pubmed:abstractText | The synthesis and SAR of a new class of piperidine-based alphavbeta3/alphavbeta5 integrin antagonists is described. Replacement of an amide bond in a prototype isonipecotamide by a C-C isostere, and adjustment of the spacer length between the carboxylic acid and basic moieties, led to low nanomolar antagonists of alphavbeta3 and/or alphavbeta5 integrins with excellent selectivity versus alpha(IIb)beta3. | lld:pubmed |
| pubmed-article:15380233 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15380233 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15380233 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15380233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15380233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15380233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15380233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15380233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15380233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15380233 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15380233 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:15380233 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:JosKK | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:MaryanoffBruc... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:KinneyWilliam... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:GhoshShyamali... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:BrunnerLiviaL | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:ToungeBrett... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:SantulliRosem... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:HoekstraWilli... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:DamianoBruce... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:BakerJudithJ | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:GalemmoRobert... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:JohnsonDana... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:De... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:TumanRobert... | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:BurnsCandaceC | lld:pubmed |
| pubmed-article:15380233 | pubmed:author | pubmed-author:ProostJef CJC | lld:pubmed |
| pubmed-article:15380233 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15380233 | pubmed:day | 18 | lld:pubmed |
| pubmed-article:15380233 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:15380233 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15380233 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15380233 | pubmed:pagination | 5227-32 | lld:pubmed |
| pubmed-article:15380233 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:meshHeading | pubmed-meshheading:15380233... | lld:pubmed |
| pubmed-article:15380233 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15380233 | pubmed:articleTitle | Piperidine-containing beta-arylpropionic acids as potent antagonists of alphavbeta3/alphavbeta5 integrins. | lld:pubmed |
| pubmed-article:15380233 | pubmed:affiliation | Drug Discovery, Johnson & Johnson Pharmaceutical Research and Development, Welsh & McKean Roads, Spring House, PA 19477-0776, USA. bdecorte@prdus.jnj.com | lld:pubmed |
| pubmed-article:15380233 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15380233 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15380233 | lld:chembl |
