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pubmed-article:15372471pubmed:abstractTextTo the authors' knowledge, no effective medical therapy currently is available for advanced chordoma. Imatinib mesylate is a tyrosine kinase inhibitor targeting platelet-derived growth factor receptor-beta (PDGFRB), BCR-ABL, and KIT.lld:pubmed
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pubmed-article:15372471pubmed:affiliationAdult Sarcoma Medical Oncology Unit, Department of Cancer Medicine, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy. paolo.casal@stitutotumori.mi.itlld:pubmed
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