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pubmed-article:15365767pubmed:abstractTextPowerful growth-inhibitory action has been shown for n-3 polyunsaturated fatty acids against colon cancer cells. We have previously described their ability to inhibit proliferation of colon epithelial cells in patients at high risk of colon cancer. In the work reported here we investigated the ability of docosahexaenoic acid (DHA) to potentiate the antineoplastic activity of 5-fluorouracil (5-FU) in p53-wildtype (LS-174 and Colo 320) and p53-mutant (HT-29 and Colo 205) human colon cancer cells.lld:pubmed
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pubmed-article:15365767pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:15365767pubmed:articleTitleDocosahexaenoic acid enhances the susceptibility of human colorectal cancer cells to 5-fluorouracil.lld:pubmed
pubmed-article:15365767pubmed:affiliationInstitute of General Pathology, Catholic University, L.go F. Vito, 1, 00168, Rome, Italy. g.calviello@rm.unicatt.itlld:pubmed
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