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pubmed-article:15365073pubmed:abstractTextThe modulation of fluorouracil (FU) by folinic acid (leucovorin [LV]) has been shown to be effective in terms of tumor response rate in patients with advanced colorectal cancer, but a meta-analysis of nine trials previously published by our group failed to demonstrate a statistically significant survival difference between FU and FU-LV. We present an update of the meta-analysis, with a longer follow-up and the inclusion of 10 newer trials.lld:pubmed
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pubmed-article:15365073pubmed:articleTitleModulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: an updated meta-analysis.lld:pubmed
pubmed-article:15365073pubmed:affiliationSaint Luc Hospital, Ireland.lld:pubmed
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