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pubmed-article:15364762pubmed:abstractTextThe renin-angiotensin system (RAS), including angiotensin-converting enzyme (ACE) and angiotensin II type 1 receptor (AT(1)R), plays an important role in the pathogenesis of pulmonary hypertension, which is suggested to be critical in the development of high-altitude pulmonary edema (HAPE). Investigating the associations of the polymorphisms in the genes of RAS with HAPE is to elucidate the genetic background underlying this disease.lld:pubmed
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pubmed-article:15364762pubmed:articleTitlePolymorphisms of renin-angiotensin system genes with high-altitude pulmonary edema in Japanese subjects.lld:pubmed
pubmed-article:15364762pubmed:affiliationDepartment of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.lld:pubmed
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