| pubmed-article:1535250 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1535250 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:1535250 | lifeskim:mentions | umls-concept:C1257909 | lld:lifeskim |
| pubmed-article:1535250 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:1535250 | lifeskim:mentions | umls-concept:C0002199 | lld:lifeskim |
| pubmed-article:1535250 | lifeskim:mentions | umls-concept:C1283195 | lld:lifeskim |
| pubmed-article:1535250 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1535250 | pubmed:dateCreated | 1992-7-29 | lld:pubmed |
| pubmed-article:1535250 | pubmed:abstractText | The bovine interferon-alpha receptor (BoIFN-alpha R) mediates the activity of bovine IFN-alpha s and IFN-beta. In addition, human IFN-alpha s have uniformly high biological activity on bovine cells. A 32P-labeled derivative of human recombinant IFN-alpha A (HuIFN-alpha A-P1) binds well and can form a characteristic 130-kDa complex on bovine cells, but not on hamster cells. We have, therefore, analyzed the binding and covalent crosslinking of [32P]HuIFN-alpha A-P1 to a panel of bovine-hamster somatic cell hybrids. Binding to several bovine-hamster hybrid cell lines was strong (about 30-50% of that seen with bovine MDBK cells) and specific. The binding correlated uniquely with bovine syntenic group U10. In several of the hybrid lines, the ability of human IFN-alpha B to enhance the expression of endogenous MHC class I molecules correlated with the binding results. We thus conclude that the bovine IFN-alpha R structural gene (locus designation IFNAR) localizes to syntenic group U10. This group includes a number of other genes whose homologs map to human Chromosome (Chr) 21. | lld:pubmed |
| pubmed-article:1535250 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1535250 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1535250 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1535250 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1535250 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1535250 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1535250 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1535250 | pubmed:issn | 0938-8990 | lld:pubmed |
| pubmed-article:1535250 | pubmed:author | pubmed-author:WomackJ EJE | lld:pubmed |
| pubmed-article:1535250 | pubmed:author | pubmed-author:LangerJ AJA | lld:pubmed |
| pubmed-article:1535250 | pubmed:author | pubmed-author:Puvanakrishna... | lld:pubmed |
| pubmed-article:1535250 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1535250 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:1535250 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1535250 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1535250 | pubmed:pagination | 237-40 | lld:pubmed |
| pubmed-article:1535250 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:meshHeading | pubmed-meshheading:1535250-... | lld:pubmed |
| pubmed-article:1535250 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1535250 | pubmed:articleTitle | Somatic cell mapping of the bovine interferon-alpha receptor. | lld:pubmed |
| pubmed-article:1535250 | pubmed:affiliation | Department of Molecular Genetics and Microbiology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway 08854-5635. | lld:pubmed |
| pubmed-article:1535250 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1535250 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:1535250 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
