| pubmed-article:15341986 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15341986 | lifeskim:mentions | umls-concept:C0009247 | lld:lifeskim |
| pubmed-article:15341986 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:15341986 | lifeskim:mentions | umls-concept:C0009806 | lld:lifeskim |
| pubmed-article:15341986 | lifeskim:mentions | umls-concept:C0282090 | lld:lifeskim |
| pubmed-article:15341986 | lifeskim:mentions | umls-concept:C1527249 | lld:lifeskim |
| pubmed-article:15341986 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:15341986 | pubmed:dateCreated | 2004-9-2 | lld:pubmed |
| pubmed-article:15341986 | pubmed:abstractText | The objective of this study was to investigate the association between constipation or laxative use and the risk of colorectal cancer in Japanese men and women. In 1990, we delivered a self-administered questionnaire to 41670 subjects who were 40-64 years old. During the seven years of follow-up, 251 incident cases of colorectal cancer were documented. Constipation was defined as a bowel movement frequency of less than daily. The multivariate relative risk (RR) of colorectal cancer for constipated subjects compared with those with daily bowel movements was 1.35 (95% Confidence Interval: 0.99-1.84). The RR for laxative users over non-users was 1.31 (0.88-1.95), and for frequent users (twice a week or more) it was 2.75 (1.48-5.09). When colorectal cancers were divided into colon cancers or rectal cancers, a significant association was found with colon cancer alone. Our results support the hypothesis that constipation or laxative use increases the risk of colon cancer. | lld:pubmed |
| pubmed-article:15341986 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15341986 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15341986 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15341986 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15341986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15341986 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15341986 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:15341986 | pubmed:issn | 0959-8049 | lld:pubmed |
| pubmed-article:15341986 | pubmed:author | pubmed-author:WatanabeTT | lld:pubmed |
| pubmed-article:15341986 | pubmed:author | pubmed-author:NakayaNN | lld:pubmed |
| pubmed-article:15341986 | pubmed:author | pubmed-author:TsujiII | lld:pubmed |
| pubmed-article:15341986 | pubmed:author | pubmed-author:KuriyamaSS | lld:pubmed |
| pubmed-article:15341986 | pubmed:author | pubmed-author:KurashimaKK | lld:pubmed |
| pubmed-article:15341986 | pubmed:author | pubmed-author:TsubonoYY | lld:pubmed |
| pubmed-article:15341986 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15341986 | pubmed:volume | 40 | lld:pubmed |
| pubmed-article:15341986 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15341986 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15341986 | pubmed:pagination | 2109-15 | lld:pubmed |
| pubmed-article:15341986 | pubmed:dateRevised | 2007-4-4 | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:meshHeading | pubmed-meshheading:15341986... | lld:pubmed |
| pubmed-article:15341986 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15341986 | pubmed:articleTitle | Constipation, laxative use and risk of colorectal cancer: The Miyagi Cohort Study. | lld:pubmed |
| pubmed-article:15341986 | pubmed:affiliation | Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2-1, Seiryo, Sendai, Japan. | lld:pubmed |
| pubmed-article:15341986 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15341986 | pubmed:publicationType | Multicenter Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15341986 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15341986 | lld:pubmed |
