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pubmed-article:15337883pubmed:abstractTextRegulator of G protein signaling 5 (RGS5), an inhibitor of Galpha(q) and Galpha(i) activation, was recently identified among genes highly expressed in smooth muscle cells (SMCs) of aorta but not vena cava. This finding prompted the hypothesis that RGS5 provides long-term G protein inhibition specific to normal arterial SMC populations and that loss of expression may in turn contribute to arterial disease.lld:pubmed
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pubmed-article:15337883pubmed:articleTitleRegulator of G protein signaling 5 marks peripheral arterial smooth muscle cells and is downregulated in atherosclerotic plaque.lld:pubmed
pubmed-article:15337883pubmed:affiliationDepartment of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.lld:pubmed
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