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pubmed-article:15335188pubmed:abstractTextA 57-year-old man was admitted with severe anemia and hypergamma globulinemia. After a diagnosis of multiple myeloma and autoimmune hemolytic anemia was made, chemotherapy rapidly decreased the M-protein level and improved his anemia with normalization of the direct Coombs test. The immunoglobulin binding to the patient's red cells was immunoglobulin G kappa chain like the myeloma M-protein. However, monoclonal immunoglobulin G derived from short-term culture of the patient's bone marrow mononuclear cells did not bind to a panel of red cells. Therefore, the relationship between the M protein produced by his myeloma cells and hemolysis remained unclear.lld:pubmed
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pubmed-article:15335188pubmed:authorpubmed-author:OtsukiTakemiTlld:pubmed
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pubmed-article:15335188pubmed:dateRevised2005-12-7lld:pubmed
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pubmed-article:15335188pubmed:year2004lld:pubmed
pubmed-article:15335188pubmed:articleTitleMultiple myeloma complicated by autoimmune hemolytic anemia.lld:pubmed
pubmed-article:15335188pubmed:affiliationDivision of Hematology, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama.lld:pubmed
pubmed-article:15335188pubmed:publicationTypeJournal Articlelld:pubmed
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