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pubmed-article:15334458pubmed:abstractTextSensitive noninvasive strategies for monitoring treatment response in rheumatoid arthritis (RA) would be valuable for facilitating appropriate therapy and dosing, evaluating clinical outcome, and developing more effective drugs. Because different proteases are highly up-regulated in RA and contribute significantly to joint destruction, in the present study we investigated whether such enzymes are suitable in vivo imaging biomarkers for early evaluation of treatment response in a murine model of RA.lld:pubmed
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pubmed-article:15334458pubmed:articleTitleIn vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response.lld:pubmed
pubmed-article:15334458pubmed:affiliationMassachusets General Hospital, Harvard Medical School, Charlestown 02129, USA.lld:pubmed
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