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pubmed-article:15328203pubmed:abstractTextIrofulven is a novel alkylating agent with promising clinical activity, particularly toward ovarian and hormone-refractory prostate cancers. To facilitate additional clinical development, we have aimed to identify biological markers associated with sensitivity to the compound.lld:pubmed
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pubmed-article:15328203pubmed:articleTitleIrofulven cytotoxicity depends on transcription-coupled nucleotide excision repair and is correlated with XPG expression in solid tumor cells.lld:pubmed
pubmed-article:15328203pubmed:affiliationGroup of Biology and Pharmacogenetics of Human Tumors, Centre National de la Recherche Scientifique, UMR 8113, Institut Gustave-Roussy, Villejuif, France.lld:pubmed
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