| pubmed-article:1531987 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0376387 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0018823 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0031809 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C1522565 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0116190 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0033095 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0449468 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:1531987 | lifeskim:mentions | umls-concept:C0443144 | lld:lifeskim |
| pubmed-article:1531987 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1531987 | pubmed:dateCreated | 1992-4-10 | lld:pubmed |
| pubmed-article:1531987 | pubmed:abstractText | Denervation of the heart involves an alteration (density, distribution of beta 1-beta 2-types) of beta-adrenoceptors in long-term follow-up. To elucidate the influence of these changes on left ventricular contractility and to provide an effective alternative treatment to re-transplantation in cases of chronic rejection (coronary vasculopathy-CVP, unspecific myocardial allograft failure-UMAF) a clinical study on 19 male transplant recipients after orthotopic heart transplantation without CVP and UMAF in the non-rejecting state was undertaken. Six male patients served as a control group to compare the systolic function at rest. Left ventricular end-systolic pressure-volume relationships (ESPVR) (k-slope) were registered and computer measured using a conductance catheter-technique under conditions of a transiently occluded vena cava and at a fixed heart rate (atrial pacing) in all patients (n = 25). In the transplanted patient group the acute response of enoximone (0.75 mg/kg) administered intravenously was recorded. The position of the ESPVR in the transplanted hearts were not different as compared to the data obtained from the non-transplanted hearts at rest. The k-slope increased from the baseline data after the acute infusion of enoximone in the transplanted hearts. The dosage of enoximone used produced a significant leftward shift in the ESPVR in most patients (89%). In addition, 42% of the patients showed an insignificant drop in left ventricular systolic pressure. Thus, the baseline contractile characteristics of the heart transplant recipients without chronic rejection and in the non-rejecting state is not obviously different from those in non-transplanted patients at rest independent of the time since operation.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:1531987 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1531987 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1531987 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1531987 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1531987 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1531987 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1531987 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1531987 | pubmed:issn | 0021-9509 | lld:pubmed |
| pubmed-article:1531987 | pubmed:author | pubmed-author:HeubleinBB | lld:pubmed |
| pubmed-article:1531987 | pubmed:author | pubmed-author:WagenbrethII | lld:pubmed |
| pubmed-article:1531987 | pubmed:author | pubmed-author:DieterichH... | lld:pubmed |
| pubmed-article:1531987 | pubmed:author | pubmed-author:HaverichAA | lld:pubmed |
| pubmed-article:1531987 | pubmed:author | pubmed-author:AuricchioAA | lld:pubmed |
| pubmed-article:1531987 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1531987 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:1531987 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1531987 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1531987 | pubmed:pagination | 21-7 | lld:pubmed |
| pubmed-article:1531987 | pubmed:dateRevised | 2009-11-11 | lld:pubmed |
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| pubmed-article:1531987 | pubmed:articleTitle | Evaluation of the inotropic function at rest and the effect of enoximone in heart transplanted recipients. Assessment by left ventricular endsystolic pressure volume relationship. | lld:pubmed |
| pubmed-article:1531987 | pubmed:affiliation | Division of Cardiology, Hannover Medical School, Germany. | lld:pubmed |
| pubmed-article:1531987 | pubmed:publicationType | Journal Article | lld:pubmed |
