| pubmed-article:15315758 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15315758 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
| pubmed-article:15315758 | lifeskim:mentions | umls-concept:C0028630 | lld:lifeskim |
| pubmed-article:15315758 | lifeskim:mentions | umls-concept:C0079904 | lld:lifeskim |
| pubmed-article:15315758 | lifeskim:mentions | umls-concept:C0178555 | lld:lifeskim |
| pubmed-article:15315758 | lifeskim:mentions | umls-concept:C0037791 | lld:lifeskim |
| pubmed-article:15315758 | lifeskim:mentions | umls-concept:C0596448 | lld:lifeskim |
| pubmed-article:15315758 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15315758 | pubmed:dateCreated | 2004-8-18 | lld:pubmed |
| pubmed-article:15315758 | pubmed:abstractText | The transcription factor NF-kappaB regulates a wide variety of genes involved in multiple processes. Although the apparent consensus sequence of DNA binding sites for NF-kappaB (kappaB sites) is very broad, the sites active in any one gene show remarkable evolutionary stability. Using a lentivirus-based methodology for implantation of gene regulatory sequences we show that for genes with two kappaB sites, both are required for activity. Swapping sites between kappaB-dependent genes altered NF-kappaB dimer specificity of the promoters and revealed that two kappaB sites can function together as a module to regulate gene activation. Further, although the sequence of the kappaB site is important for determining kappaB family member specificity, rather than determining the ability of a particular dimer to bind effectively, the sequence affects which coactivators will form productive interactions with the bound NF-kappaB dimer. This suggests that binding sites may impart a specific configuration to bound transcription factors. | lld:pubmed |
| pubmed-article:15315758 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15315758 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15315758 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15315758 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:15315758 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:15315758 | pubmed:author | pubmed-author:BaltimoreDavi... | lld:pubmed |
| pubmed-article:15315758 | pubmed:author | pubmed-author:HoffmannAlexa... | lld:pubmed |
| pubmed-article:15315758 | pubmed:author | pubmed-author:LeungThomas... | lld:pubmed |
| pubmed-article:15315758 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15315758 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:15315758 | pubmed:volume | 118 | lld:pubmed |
| pubmed-article:15315758 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15315758 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15315758 | pubmed:pagination | 453-64 | lld:pubmed |
| pubmed-article:15315758 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:meshHeading | pubmed-meshheading:15315758... | lld:pubmed |
| pubmed-article:15315758 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15315758 | pubmed:articleTitle | One nucleotide in a kappaB site can determine cofactor specificity for NF-kappaB dimers. | lld:pubmed |
| pubmed-article:15315758 | pubmed:affiliation | Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA. | lld:pubmed |
| pubmed-article:15315758 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15315758 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| entrez-gene:2033 | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| entrez-gene:3627 | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| entrez-gene:3661 | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| entrez-gene:4790 | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| entrez-gene:5970 | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| entrez-gene:18033 | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15315758 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15315758 | lld:pubmed |
