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pubmed-article:15275266pubmed:abstractTextUntil recently, the transmission of tick-borne pathogens via vertebrates was thought to depend on the development of a systemic infection in the vertebrate hosts. Pathogen transmission has now been shown to occur between infected and uninfected ticks co-feeding in time or space in the absence of a systemic infection, originally for viruses, but now also for bacteria. The epidemiological consequences of this new non-systemic transmission pathway necessitate a major reassessment of the components and dynamics of tick-borne pathogen enzootic cycles. Here Sarah Randolph, Lise Gern and Pat Nuttall show that a much wider range of natural hosts than was previously recognized may contribute significantly to the transmission of tick-borne diseases, and compare quantitatively the relative contributions made by the systemic and non-systemic transmission pathways.lld:pubmed
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pubmed-article:15275266pubmed:pagination472-9lld:pubmed
pubmed-article:15275266pubmed:dateRevised2009-9-29lld:pubmed
pubmed-article:15275266pubmed:year1996lld:pubmed
pubmed-article:15275266pubmed:articleTitleCo-feeding ticks: Epidemiological significance for tick-borne pathogen transmission.lld:pubmed
pubmed-article:15275266pubmed:affiliationDepartment of Zoology, South Parks Road, Oxford, UK. sarah.randolph@zoology.ox.ac.uklld:pubmed
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