Virtually complete control of simple and face diastereoselectivity in the Michael addition reactions between achiral equivalents of a nucleophilic glycine and (S)- or (R)-3-(E-enoyl)-4-phenyl-1,3-oxazolidin-2-ones: practical method for preparation of beta-substituted pyroglutamic acids and prolines.

Source:http://linkedlifedata.com/resource/pubmed/id/15255725

J. Org. Chem. 2004 Jul 23 69 15 4984-90

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15255725