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pubmed-article:15249729pubmed:abstractTextChronic stress is characterized by an increased activity of the hypothalamic-pituitary-adrenocortical axis and decreased humoral and cell-mediated immune responses. In the rat, corticosterone is the principal natural immune suppressor. Neurointermediate pituitary lobectomy (NIL) in rats induces diabetes insipidus and protracted increases in basal adrenocorticotropin and corticosterone plasma levels, a situation that resembles chronic stress. In this paper, we evaluated the effects of NIL on humoral (hemagglutinin titers and footpad swelling to sheep red blood cells--SRBC) and cell-mediated immune responses (contact hypersensitivity to dinitrochlorobenzene).lld:pubmed
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pubmed-article:15249729pubmed:authorpubmed-author:KovacsKalmanKlld:pubmed
pubmed-article:15249729pubmed:authorpubmed-author:Quintanar-Ste...lld:pubmed
pubmed-article:15249729pubmed:authorpubmed-author:BercziIstvanIlld:pubmed
pubmed-article:15249729pubmed:copyrightInfoCopyright 2004 S. Karger AG, Basellld:pubmed
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pubmed-article:15249729pubmed:articleTitleEffects of neurointermediate pituitary lobectomy on humoral and cell-mediated immune responses in the rat.lld:pubmed
pubmed-article:15249729pubmed:affiliationDepartamento de Fisiología y Farmacología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico. aquinta@correo.uaa.mxlld:pubmed
pubmed-article:15249729pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15249729pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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