| pubmed-article:15225294 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C0040558 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C0030498 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C0030664 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C0021758 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C2828008 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C0851827 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C1701901 | lld:lifeskim |
| pubmed-article:15225294 | lifeskim:mentions | umls-concept:C0445356 | lld:lifeskim |
| pubmed-article:15225294 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:15225294 | pubmed:dateCreated | 2004-6-30 | lld:pubmed |
| pubmed-article:15225294 | pubmed:abstractText | The role of interleukin-4 (IL-4) during the course of Toxoplasma gondii infection was studied using IL-4-/- mice and their wild-type (WT) counterparts on a C57BL/6 background. Following oral infection with T. gondii tissue cysts an exacerbative role for IL-4 was demonstrated and IL-4-/- mice were found to be more resistant to infection than WT mice as measured by significantly reduced mortality. Furthermore pathology in the small intestine was less severe in IL-4-/- mice although conversely liver pathology was greater than in wild-type mice. Significantly, plasma IL-12 and IFN-gamma levels, which peaked at days 6 and 8, respectively, were higher in IL-4-/- mice. The exacerbatory role of IL-4 in the intestine was found by competitive RT-PCR not to be associated with increased parasite burdens but was related to comparative expression of IL-10. | lld:pubmed |
| pubmed-article:15225294 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15225294 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15225294 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15225294 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15225294 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15225294 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15225294 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:15225294 | pubmed:issn | 0141-9838 | lld:pubmed |
| pubmed-article:15225294 | pubmed:author | pubmed-author:AlexanderJJ | lld:pubmed |
| pubmed-article:15225294 | pubmed:author | pubmed-author:RobertsFF | lld:pubmed |
| pubmed-article:15225294 | pubmed:author | pubmed-author:LyonsR ERE | lld:pubmed |
| pubmed-article:15225294 | pubmed:author | pubmed-author:RobertsC WCW | lld:pubmed |
| pubmed-article:15225294 | pubmed:author | pubmed-author:HunterC ACA | lld:pubmed |
| pubmed-article:15225294 | pubmed:author | pubmed-author:BrombacherFF | lld:pubmed |
| pubmed-article:15225294 | pubmed:author | pubmed-author:NickdelM BMB | lld:pubmed |
| pubmed-article:15225294 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15225294 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:15225294 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15225294 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15225294 | pubmed:pagination | 75-82 | lld:pubmed |
| pubmed-article:15225294 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:meshHeading | pubmed-meshheading:15225294... | lld:pubmed |
| pubmed-article:15225294 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15225294 | pubmed:articleTitle | Intestinal pathology during acute toxoplasmosis is IL-4 dependent and unrelated to parasite burden. | lld:pubmed |
| pubmed-article:15225294 | pubmed:affiliation | Department of Immunology, Strathclyde Institute for Biomedical Sciences, University of Strathclyde, Glasgow, UK. | lld:pubmed |
| pubmed-article:15225294 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15225294 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:16189 | entrezgene:pubmed | pubmed-article:15225294 | lld:entrezgene |
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