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pubmed-article:15214906pubmed:abstractTextTopical corticosteroids decrease collagen synthesis during short-term treatment and can induce skin atrophy when applied over the long term. In contrast, short-term tacrolimus ointment therapy does not affect collagen synthesis.lld:pubmed
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pubmed-article:15214906pubmed:articleTitleEffects of 1-year intermittent treatment with topical tacrolimus monotherapy on skin collagen synthesis in patients with atopic dermatitis.lld:pubmed
pubmed-article:15214906pubmed:affiliationDepartment of Dermatology, Hospital for Skin and Allergic Diseases, University of Helsinki, 00250, Finland.lld:pubmed
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